The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.

Aliases：    HPRT; HGPRT    

Entrez GeneID：    3251    

Swissprot：    P00492      

WB Predicted band size：    24.6kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human HPRT1 (AA: FULL(1-218)) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000