Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Aliases ：   GUCA3; GC-SA3; GUC1A3; GUCSA3; GUCY1A1    

Entrez GeneID ：   2982    

Swissprot ：   Q02108      

WB Predicted band size ：   77.5kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen  ：  Purified recombinant fragment of human GUCY1A3 (AA: 22-214) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000