Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.

Aliases：    EAA5; GLR7; GLUR7; GluK3; GluR7a    

Entrez GeneID：    2899    

Swissprot：    Q13003     

WB Predicted band size：    104kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human GRIK3 (AA: extra 32-173) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000