This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants.
Aliases: BFPP; BPPR; ADGRG1; TM7LN4; TM7XN1
Entrez GeneID : 9289
Swissprot: Q9Y653
WB Predicted band size: 77.7kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human GPR56 (AA: extra(26-225)) expressed in E. Coli.