The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. (provided by RefSeq)
Aliases: FLJ39408; 1110046B12Rik
Entrez GeneID: 197258
Swissprot : Q8N0W3
WB Predicted band size: 117kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human,Mouse,Rat,Monkey
Immunogen: Purified recombinant fragment of human FUK expressed in E. Coli.