This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Aliases：    EWSR2; SIC-1; BDPLT21    

Entrez GeneID：    2313    

Swissprot：    Q01543    

WB Predicted band size：    50.9kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity：   Human    

Immunogen ：   Purified recombinant fragment of human FLI1 (AA: 303-452) expressed in E. Coli.    

IHC    1/200-1/1000    

FCM    1/200-1/400    

ELISA    1/10000