This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
Aliases: FCRN; alpha-chain
Entrez GeneID: 2217
Swissprot: P55899
WB Predicted band size: 39.7kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human FCGRT (AA: extra 24-297) expressed in E. Coli.