The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Aliases：    CVL; CVIL; VIL2; HEL-S-105    

Entrez GeneID：    7430    

Swissprot ：   P15311    

WB Predicted band size：    69.4kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human,Mouse,Monkey    

Immunogen：    Purified recombinant fragment of human EZR (AA: 292-464) expressed in E. Coli.    

WB    1/500 - 1/2000    

IF/ICC    1/100 - 1/400    

FCM    1/200 - 1/400    

ELISA    1/10000