The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. (provided by RefSeq) Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts

Aliases:    ERK3; PRKM6; p97MAPK; HsT17250; DKFZp686F03189; MAPK6    

Entrez GeneID:    5597    

Swissprot:    Q16659    

WB Predicted band size:    105kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity :   Human    

Immunogen:    Purified recombinant fragment of human ERK3 expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000