Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).
Aliases: EIF-5; EIF-5A
Entrez GeneID : 1983
Swissprot : P55010
WB Predicted band size: 49.2kDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human EIF5 (AA: 1-300) expressed in E. Coli.