The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Aliases :   ERBB; HER1; mENA; ERBB1; PIG61    

Entrez GeneID:    1956    

Swissprot:    P00533       

WB Predicted band size:    175kDa    

Host/Isotype:    Mouse IgG1    

Species Reactivity:    Human    

Immunogen :   Purified recombinant fragment of human EGFR (AA: 693-893) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000