Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

Aliases：    RIG; REIC    

Entrez GeneID：    27122    

Swissprot：    Q9UBP4    

WB Predicted band size ：   38kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Monkey    

Immunogen：    Purified recombinant fragment of human DKK3 expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000