DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
Aliases: RIGI; RIG-I; RLR-1; SGMRT2
Entrez GeneID: 23586
Swissprot: O95786
WB Predicted band size: 106.6kDa
Host/Isotype : Mouse IgM
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human DDX58 (AA: 789-925) expressed in E. Coli.