This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Aliases ：   EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2    

Entrez GeneID：    1540    

Swissprot ：   Q9NQC7      

WB Predicted band size：    107.3kDa    

Host/Isotype：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human CYLD (AA: 204-358) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000