Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Aliases : V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
Entrez GeneID: 1524
Swissprot: P49238
WB Predicted band size : 40.4kDa
Host/Isotype : Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CX3CR1 (AA: extra mix) expressed in E. Coli.