This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Aliases：    CPSD; CLN10; HEL-S-130P    

Entrez GeneID ：   1509    

Swissprot ：   P07339     

WB Predicted band size：    44.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human CTSD (AA: 1-100) expressed in E. Coli.    

IHC    1/200 - 1/1000    

ELISA    1/10000