Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.
Aliases ： COX4; COXIV; COX4-1; MGC72016; COX4I1
Entrez GeneID： 1327
Swissprot ： P13073
WB Predicted band size： 19kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human,Mouse,Rat,Monkey
Immunogen： Purified recombinant fragment of human COX4I1 expressed in E. Coli.
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