This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
Aliases: KAT13D; bHLHe8; KIAA0334; CLOCK
Entrez GeneID: 9575
Swissprot: O15516
WB Predicted band size: 95kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CLOCK expressed in E. Coli.