This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Aliases： CLEC12A; MICL; CD371; CLL-1; DCAL-2
Entrez GeneID： 160364
Swissprot ： Q5QGZ9
WB Predicted band size： 30.8kDa
Host/Isotype： Mouse IgG2a
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human CLL1 (AA: extra 65-265) expressed in E. Coli.
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