C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Aliases ：   PBT; SCFR; C-Kit; CD117; KIT    

Entrez GeneID：    3815    

Swissprot：    P10721    

WB Predicted band size：    145kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of C-kit expressed in E. Coli.    

IHC    1/200 - 1/1000    

ELISA    1/10000