Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Aliases：    ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS    

Entrez GeneID ：   1145    

Swissprot：    Q04844     

WB Predicted band size：    54.7kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Rat    

Immunogen：    Purified recombinant fragment of human CHRNE (AA: extra 21-239) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000