Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Aliases： EFNL3; nAChRB2
Entrez GeneID： 1141
Swissprot： P17787
WB Predicted band size： 57kDa
Host/Isotype： Mouse IgG2a
Species Reactivity ： Human
Immunogen： Purified recombinant fragment of human CHRNB2 (AA: extra 26-233) expressed in E. Coli.
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