This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.

Aliases：    CHNRA6    

Entrez GeneID：    8973    

Swissprot：    Q15825    

WB Predicted band size：    57kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human CHRNA6 (AA: 26-239) expressed in E. Coli.    

IHC    1/200 - 1/1000    

IF/ICC    1/100 - 1/500    

FCM    1/200 - 1/400    

ELISA    1/10000