The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).
Aliases: LNCR2
Entrez GeneID: 1138
Swissprot: P30532
WB Predicted band size: 53kDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human,Rat
Immunogen: Purified recombinant fragment of human CHRNA5 (AA: extra 23-254) expressed in E. Coli.