The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
Aliases： HM3; PBS; EGBRS
Entrez GeneID： 1131
Swissprot： P20309
WB Predicted band size： 66kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human CHRM3 (AA: extra mix) expressed in E. Coli.
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