The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
Aliases： CGA
Entrez GeneID： 1113
Swissprot： P10645
WB Predicted band size： 50kDa
Host/Isotype ： Mouse IgG2b
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human CHGA (AA: 278-457) expressed in E. Coli.
WeChat
