The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

Aliases：    CASH; FLIP; MRIT; CLARP; FLAME; Casper; FLAME1; c-FLIP; FLAME-1; I-FLICE; c-FLIPL; c-FLIPR; c-FLIPS; CASP8AP1    

Entrez GeneID：    8837    

Swissprot：    O15519    

WB Predicted band size ：   55kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity：    Human,Mouse    

Immunogen：    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.    

WB    1/500 - 1/2000    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000