This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
Aliases: CEA; CGM1; W264; W282; CD66D
Entrez GeneID : 1084
Swissprot: P40198
WB Predicted band size : 27kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human,Rat
Immunogen : Purified recombinant fragment of human CEACAM3 (AA: 35-155) expressed in E. Coli.