The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Aliases： CDC2; CDC28A; P34CDC2; MGC111195; DKFZp686L20222; CDK1
Entrez GeneID： 983
Swissprot： P06493
WB Predicted band size： 34kDa
Host/Isotype： Mouse IgG1
Species Reactivity ： Human,Mouse,Rat,Monkey
Immunogen ： Purified recombinant fragment of human CDK1 expressed in E. Coli.
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