This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Aliases : CDHN; NCAD; CD325; CDw325; CDH2
Entrez GeneID : 1000
Swissprot : P19022
WB Predicted band size: 99.8kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse,Rat,Rabbit,Monkey
Immunogen : Purified recombinant fragment of human CDH2 expressed in E. Coli.