The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Aliases：    ITGA5; FNRA; VLA-5; VLA5A    

Entrez GeneID：    3678    

Swissprot ：   P08648    

WB Predicted band size：    114.5kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：   Human    

Immunogen：    Purified recombinant fragment of human CD49E (AA: extra 111-253) expressed in E. Coli.    

ELISA    1/10000