The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.

Aliases：    ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3    

Entrez GeneID：    3675    

Swissprot：    P26006    

WB Predicted band size：    116.6kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human CD49C (AA: extra 63-248) expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000