This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Aliases ：   ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2    

Entrez GeneID：   3673    

Swissprot ：   P17301    

WB Predicted band size ：   129.3kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.    

IF/ICC    1/100 - 1/500    

FCM    1/200 - 1/400    

ELISA    1/10000