The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Aliases : CVID; RYZN; TACI; CD267; CVID2; IGAD2; TNFRSF14B
Entrez GeneID: 23495
Swissprot: O14836
WB Predicted band size: 31.8kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CD267 (AA: extra(1-165)) expressed in E. Coli.