This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases: 2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Entrez GeneID : 51744
Swissprot : Q9BZW8
WB Predicted band size: 41.6kDa
Host/Isotype : Mouse IgG2b
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human CD244 (AA: 22-229) expressed in E. Coli.