This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Aliases ：   PTA1; DNAM1; DNAM-1; TLiSA1    

Entrez GeneID：   10666    

Swissprot ：   Q15762     

WB Predicted band size：    38.6kDa    

Host/Isotype：    Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human CD226 (AA: extra 19-254) expressed in E. Coli.    

IHC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000