Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases ：   IL17RA; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R    

Entrez GeneID：    23765    

Swissprot：    Q96F46     

WB Predicted band size：    96.1kDa    

Host/Isotype：    Mouse IgG2b    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human CD217 (AA: extra 33-320) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000