This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Aliases :   MRC; MOX1; MOX2; OX-2    

Entrez GeneID :   4345    

Swissprot :   P41217    

WB Predicted band size:    31.3kDa    

Host/Isotype:    Mouse IgG2a    

Species Reactivity:    Human    

Immunogen:    Purified recombinant fragment of human CD200 (AA:Extra(31-232)) expressed in E. Coli.    

IF/ICC    1/200 - 1/1000    

FCM    1/200 - 1/400    

ELISA    1/10000