The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.

Aliases ：   CCR2; CKR2; CCR-2; CCR2A; CCR2B; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2    

Entrez GeneID：    729230    

Swissprot ：   P41597     

WB Predicted band size：    41.9kDa    

Host/Isotype：    Mouse IgG1     

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human CD192 expressed in E. Coli.    

WB    1/500 - 1/2000    

FCM    1/200 - 1/400    

ELISA    1/10000