The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.

Aliases ：   VPREB1; IGI; IGVPB; VPREB    

Entrez GeneID：    7441    

Swissprot：    P12018      

WB Predicted band size ：   16.6kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity：    Human    

Immunogen：    Purified recombinant fragment of human CD179A (AA: extra 20-145) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000