The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
Aliases: FCGR3B; CD16; FCG3; CD16A; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb
Entrez GeneID: 2215
Swissprot : O75015
WB Predicted band size: 26.2kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Purified recombinant fragment of human CD16B (AA: 17-200) expressed in E. Coli.