Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.
Aliases : KLRB1; NKR; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A
Entrez GeneID: 3820
Swissprot : Q12918
WB Predicted band size: 25.4kDa
Host/Isotype: Mouse IgG2b
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human CD161 (AA: extra 67-225) expressed in E. Coli.
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