This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
Aliases： ADAM8; MS2; CD156a
Entrez GeneID： 101
Swissprot： P78325
WB Predicted band size： 88.8kDa
Host/Isotype ： Mouse IgG2a
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human CD156 (AA: extra 17-156) expressed in E. Coli.
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