The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases：    PVR; PVS; HVED; NECL5; TAGE4; Necl-5    

Entrez GeneID：    5817    

Swissprot ：   P15151    

WB Predicted band size ：   45.3kDa    

Host/Isotype ：   Mouse IgG1    

Species Reactivity ：   Human    

Immunogen：    Purified recombinant fragment of human CD155 (AA: 21-343) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000