The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.

Aliases：    THBD; TM; THRM; AHUS6; BDCA3; THPH12    

Entrez GeneID：    7056    

Swissprot ：   P07204      

WB Predicted band size：    60.3kDa    

Host/Isotype：   Mouse IgG1     

Species Reactivity：    Human    

Immunogen ：   Purified recombinant fragment of human CD141 (AA: extra 297-505) expressed in E. Coli.    

FCM    1/200 - 1/400    

ELISA    1/10000